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Tridenosen Injection

VET ONLY PRODUCT - Vasodilator to improve blood flow and minimise tying-up/cramping, fatigue and muscle damage in Horses and Dogs
COMPOSITION
Each mL contains:
Adenosine triphosphate (ATP) 2 mg
Nicotinic acid 20 mg
Magnesium aspartate 20 mg
Potassium aspartate 20 mg
Di-isopropylamine dichloroacetate (DADA) 50 mg
Sodium selenite 500 μg
Actions
TRIDENOSEN is a potent dilator of the small arteries of the muscles of the body and heart. Adenosine, Nicotinic acid and DADA all dilate blood vessels that supply muscles. The reduction in vascular resistance produced by these agents leads to an increase in ease of blood flow, oxygen supply, and muscle perfusion. This increased blood flow leads to increased CO2 and lactic acid removal, reducing fatigue and muscle damage during maximal work periods. Experimental studies show that the blood supply to heart muscle
is increased by more than 100% by infusion with adenosine compounds; and to skeletal muscle by 92%.
Magnesium and potassium aspartates are used in the treatment of fatigue and exhaustion in humans, and of the sodium / potassium imbalance which accompanies these fatigue states.
Selenium and potassium aspartates are potent anti-oxidants, and help to limit muscle damage or azoturia incurred as a result of strenuous work . TRIDENOSEN has been shown in clinical trials to reduce post-exercise CPK and SGOT levels, indicating that less muscle cell damage has been incurred.
Indications
TRIDENOSEN should be used to prevent cramping and Tying Up (Rhabdomyolysis or azoturia). It can be successfully used to counter fatigue states, and as an aid to recovery after hard work.
TRIDENOSEN is of value in cases of "heart strain" as evidenced by ECG T wave changes.
Form
Injectable
Category
Cardiovascular System, Bloods
Performance, Work Tolerance
Muscle Damage, Tying Up
Recovery
Anti-Oxidants
For
Horse
Dog


 
Dosage and Administration
Horse: Adult: 15 - 25 mL once or twice weekly
Foal: 5 mL once or twice weekly
Dogs: 2 - 5 mL once or twice weekly
Administer TRIDENOSEN by intramuscular injection, or slow intravenous injection under the direction of a veterinary surgeon.
Presentation
100 mL sterile multi-dose glass vial
Storage
Store below 25˚ C (Air Conditioning). Protect from light.
Availability
S4 - By Veterinary Prescription (APVMA 51223)
Notes

Also see
AMP-5, Tripart, DADA 250, Untie, L-carnitine
Warnings
Do not administer vasodilating agents to animals in shock.
Meat Withholding Period (Horses): 28 Days


 

 
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